OC-089 Epigenetic Control of GI Inflammation Via the Methyl-Binding Protein MBD2
نویسندگان
چکیده
منابع مشابه
An Epigenetic Regulator: Methyl-CpG-Binding Domain Protein 1 (MBD1)
DNA methylation is an important form of epigenetic regulation in both normal development and cancer. Methyl-CpG-binding domain protein 1 (MBD1) is highly related to DNA methylation. Its MBD domain recognizes and binds to methylated CpGs. This binding allows it to trigger methylation of H3K9 and results in transcriptional repression. The CXXC3 domain of MBD1 makes it a unique member of the MBD f...
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ژورنال
عنوان ژورنال: Gut
سال: 2013
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2013-304907.088